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quinazoline - traduction vers arabe
![[[Gefitinib]] for treatment of [[non-small-cell lung carcinoma]].](https://commons.wikimedia.org/wiki/Special:FilePath/Gefitinib structure.svg?width=200 "[[Gefitinib]] for treatment of [[non-small-cell lung carcinoma]].")
![[[Lapatinib]] for treatment of advanced-stage or metastatic breast cancer.](https://commons.wikimedia.org/wiki/Special:FilePath/Lapatinib.svg?width=200 "[[Lapatinib]] for treatment of advanced-stage or metastatic breast cancer.")
![[[Erlotinib]], an anti-tumor agent.](https://commons.wikimedia.org/wiki/Special:FilePath/Erlotinib.svg?width=200 "[[Erlotinib]], an anti-tumor agent.")
![[[Afatinib]] for treatment of cancers resistant to gefinitib and erlotinib.](https://commons.wikimedia.org/wiki/Special:FilePath/Afatinib skeletal.svg?width=200 "[[Afatinib]] for treatment of cancers resistant to gefinitib and erlotinib.")
Wikipédia
Quinazoline is an organic compound with the formula C8H6N2. It is an aromatic heterocycle with a bicyclic structure consisting of two fused six-membered aromatic rings, a benzene ring and a pyrimidine ring. It is a light yellow crystalline solid that is soluble in water. Also known as 1,3-diazanaphthalene, quinazoline received its name from being an aza derivative of quinoline. Though the parent quinazoline molecule is rarely mentioned by itself in technical literature, substituted derivatives have been synthesized for medicinal purposes such as antimalarial and anticancer agents. Quinazoline is a planar molecule. It is isomeric with the other diazanaphthalenes of the benzodiazine subgroup: cinnoline, quinoxaline, and phthalazine. Over 200 biologically active quinazoline and quinoline alkaloids are identified.
